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Investigating ischemia and reperfusion-induced organ damage in severe cardiac arrest: A comprehensive proteomics perspective
Journal article   Open access   Peer reviewed

Investigating ischemia and reperfusion-induced organ damage in severe cardiac arrest: A comprehensive proteomics perspective

Ju Yeon Lee, Muhammad Shoaib, Jin-Woong Choi, Rishabh C. Choudhary, Tai Yin, Nara Yoon, Kei Hayashida, Seunguk J. Baek, Santiago J. Miyara, Lance B. Becker, …
Journal of pharmaceutical analysis, Vol.14(3), pp.427-430
03/2024
PMID: 38618246

Abstract

[Display omitted] •Proteomics analysis was used to explore post-cardiac arrest (CA) pathology.•Significant protein alterations specific to each organ were observed.•The study provides proteomic evidence for impaired brain function after CA.•The data suggest that sustained energy supply is crucial for neuroprotection.
url
https://doi.org/10.1016/j.jpha.2023.09.017View
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